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TOPICS IN BIOMEDICAL GERONTOLOGY

Pramod C. Sharma Ram Rath

Oprawa:
TWARDA

Wydawca:
Springer Singapore

ISBN:
9789811021541

1 201,15 PLN
Wysyłamy w 28 dni

Opis produktu

This book presents a collection of articles on various aspects of current research on aging. These include model systems cellular biochemical and molecular aspects of experimental aging research as well as selected intervention studies on agerelated diseases./Aging is a global challenge to human society. Children are always in a hurry to become adults while adults produce offspring and add to the gene pool. However after adulthood or the attainment of reproductive maturity all physiological parameters of the living organism start to undergo the aging process. Old age sets in slowly but surely and usually continues for a prolonged period. If vigor and vitality are the main advantages of adulthood old age offers the rewards of experience and maturity.br/Biologists ask questions such as: Why do we age? How do we become old? Is it possible to slow down postpone or even prevent aging? In turn medical experts ask: What are the diseases associated with old age? Are there medicines that can help affected elderly patients? In fact both groups are asking themselves how can we add more health to old age.br/Healthy aging is the dream of every individual. But to achieve this it is fundamental that we first understand the cellular biochemical and molecular basis of the aging process in mammalian cells tissues and intact living organisms which can serve as experimental model systems in Biomedical Gerontology. Once the biology of aging is understood at the genetic and molecular levels interventional approaches to aging and its associated diseases may be easier to plan and implement at the preclinical level.div1. Identification of serum sirtuins as novel noninvasive protein markers for frailty. 2.Agerelated morphological changes in the human pancreas. 3.Changing population of neurons and glia in the human cochlear nucleus during aging. 4.Agerelated changes in the expression level of insulinlike growth factor1 and its related signaling pathway in mice. 5.Differential expression of arginase I and its regulation by dexamethasone in the liver of mice as a function of age. 6.Molecular and cellular basis of memory enhancing effects ofBacopa monnieri extract on diabetes mellitus induced memory impairment in mice. 7.Brain aging and oxidative pathology. 8.Antiepileptic potential of dehydroepiendrosterone (DHEA). 9.Curcumin attenuates memory impairment by modulating the expression of CamKII during aging. 10.Dietary restriction an intervention for healthy aging. 11.Study of antiageing property of moringaoleifera leaves in fish brain. 12.Alterations in the structure and function of the chromatin during aging. 13.Postnatal exposure of PBDE209 impairs spatial memory in young mice:Relation of glutamate and oxidantantioxidant homeostasis in the frontal cortex and hippocampus. 14.Differential expression of long intergenic noncoding RNA (lincRNA) in the rat brain during aging. 15.Dietary restriction upregulates expression and activity of cardiac and skeletal

Wymiary: 6919 gr 155 mm 235 mm

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