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HANDBOOK OF NEUROTOXICITY

Richard M. Kostrzewa

Oprawa:
TWARDA

Wydawca:
Springer New York

ISBN:
9781461458357

3 707,34 PLN
Wysyłamy w 28 dni

Opis produktu

The Handbook of Neurotoxicity is a reference source for identifying characterizing instructing on use and describing outcomes of neurotoxin treatments to understand mechanisms associated with toxin use: to project outcomes of neurotoxin treatments: to gauge neurotoxins as predictors of events leading to neurodegenerative disorders and as aids to rational use of neurotoxins to model disease entities. Neuroprotection is approached in different manners includingthose 1) afforded by therapeutic agents clinical and preclinical: or 2) by nondrug means such as exercise. The amorphous term śneurotoxin is discussed in terms of the possible eventuality of a neuroprotectant producing an outcome of excess neuronal survival and a behavioral spectrum that might produce a dysfunction akin to a neurotoxins effect. The Handbook of Neurotoxicity is thus an instructive and valuable guide towards understanding the role of neurotoxins/neurotoxicity in the expansive field of Neuroscience and is an indispensable tool for laboratory investigators neuroscientists and cliniHere is an instructive and valuable guide towards understanding the role of neurotoxins/neurotoxicity in the expansive field of Neuroscience. It is an indispensable tool for laboratory investigators neuroscientists and clinical researNeurotoxins: Survey of Selective Neurotoxins. Necroptosis a potential therapeutic target for neurological disorders. Cell System for Identifying Dopaminergic Neurotoxicity. Microglia: Neuroprotective and Neurodestructive Properties. 6Hydroxydopamine Lesioning of Dopamine Neurons in Neonatal and Adult Rats Induces AgeDependent Consequences. Dopamine and LDOPA as Selective Endogenous Neurotoxins. Nature of DSP4Induced Neurotoxicity. MPTP Neurotoxicity: Actions Mechanisms and Animal Modeling of Parkinsons disease. Cocaine as a Neurotoxin.br7656 and 57Dihydroxytryptamines as Serotoninergic Neurotoxins. 2NH2MPTP: A Serotonin and Norepinephrine Neurotoxin. Methamphetamine and MDMA neurotoxicity: Biochemical and molecular mechanisms. Glutamate as a Neurotoxin. Domoic acid as a Neurotoxin. Endogenous Kynurenic acid and Neurotoxicity. Neurotoxicity in psychostimulant and opiate addiction. Molecular Mechanism and Effects of Clostridial Neurotoxins. Botulinum neurotoxins as therapeutics.Neurotoxic Effects Mechanisms and Outcome of 192IgG Saporin. TRPV1 activators (vanilloids) as neurotoxins. Part 2: Dopamine Chemistry & Parkinson Disease. 6Hydroxydopamine as preclinical model of Parkinsons disease. Advances in stem cell research for Parkinson disease.Alpha synuclein in Parkinsons Disease. Autophagic pathways and Parkinson disease. Dopaminergic neurons in Parkinsons disease. Iron Neurotoxicity in Parkinsons Disease. Links between paraquat and Parkinsons disease. Manganese neurotoxicity. Mechanisms of dopamine oxidation and Parkinsons Disease. Neuroinflammation and Parkinsons Disease. Neuromelanin and Parkinsons disease. Neurotoxicity of 1m

Wymiary: 4346 gr 155 mm 235 mm

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